It has a more predictable pharmacology, but the evidence is not yet in. Which is akin to stating it is funnier than the MIMS – it’s a low bar. Tapentadol is probably better than tramadol. ![]() This is definitely one to watch carefully when prescribing. The risk of developing tolerance and potential for abuse or diversion is likely to be similar to other opiates once the word gets out. Tapentadol side effects are predictable: constipation, nausea and vomiting with some dizziness in up to a third of patients. It needs to be avoided for at least two weeks after ceasing monoamine oxidase inhibitors (MAOIs) such as moclobemide (though this is rarely used in Australia). We need to see some real-world safety data and clinical outcome studies to say exactly how much benefit this drug has.Īs with any potent opioid, tapentadol is to be used with caution in patients with respiratory failure, other sedatives or noradrenergic agents. In the trials used to get it registered, the drug was only just better than a placebo for chronic pain. The biggest issue is that there is just not enough data available about the safety or efficacy of tapentadol. But there must be a catch, right? There always is. A cleaner, direct-acting opioid with fewer side effects.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |